BONE MARROW MESENCHYMAL STEM CELL-DERIVED EXOSOMES ACCELERATE FUNCTIONAL RECOVERY AFTER SPINAL CORD INJURY BY PROMOTING THE PHAGOCYTOSIS OF MACROPHAGES TO CLEAN MYELIN DEBRIS

Macrophage phagocytosis contributes predominantly to processing central nervous system (CNS) debris and further facilitates neurological function restoration after CNS injury.The aims of this study were to evaluate the effect of bone marrow mesenchymal stem cells (BMSC)-derived exosomes (BMSC-Exos) on the phagocytic capability of macrophages to cle

Abstract Background Clinical decision support systems (CDSS) have been utilized as a low-cost intervention to improve healthcare process measures.Thus, we aim to estimate CDSS efficacy to optimize adherence to oral anticoagulant guidelines in eligible patients with atrial fibrillation (AF).Methods A systematic review and meta-analysis of randomized

Abstract Background Vacuolar H+-ATPase (V-ATPase) is a vital protein complex involved in abiotic stress response in plants.The G subunit of Juglans regia (JrVHAG1) was previously identified as a drought tolerance-related gene involved in the ABA (abscisic acid)-signal pathway.Heavy metal stress is becoming a major detriment for plant growth, develo

Abstract The vagus nerve (VN) extensively innervates the gastric enteric nervous system (ENS), but its influence on gastric ENS functionality and motility in vivo remains unclear due to technical challenges.Here we describe a method for stable, long-term observation of gastric ENS activity and muscle dynamics at cellular resolution, which can also

Aim: This study aimed to characterize the genetic diversity, evolutionary level, and prevalence of genotypes of common isolates of Salmonella (Salmonella Enteritidis and Salmonella Typhimurium).Using one of the most advanced molecular recognition techniques, multilocus variable number of tandem repeat analysis (MLVA), we characterized the genotype